TRADITIONAL SYSTEMS OF MEDICINE
Our products contain high quality natural ingredients that have numerous medicinal properties and have been tested by millions over a century since our inception.
Uses and Known Pharmacological Properties/Benefits
Eucalyptus Oil (EO) is the generic name for distilled oil from the leaf of Eucalyptus. It is endowed with antibacterial activities as well as anti-inflammatory and antioxidant properties. The eucalyptus used in herbal products is rich in 1,8-cineole.
Antimicrobial Activity of Eucalyptus
EO (Antibacterial/Antifungal/Antibacterial)
Eucalyptus EO has antimicrobial activity against viruses, bacteria, yeasts, and filamentous fungi. Eucalyptus EO, rich in 1,8-cineole (88%), was active against HSV-1 in vitro. It was able to suppress viral multiplication by >96%. It also displayed 100% inhibitory activity at 3.1 µL/mL concentration against influenza virus A1/Denver/1/57 (H1N1) after 10 min exposure
Antibacterial activity has been determined to a much greater extent. It is active, for example, against bacteria such as Porphyromonas gingivalis and S. mutant, which cause periodontitis and other dental ailments. Therefore, its main component 1,8-cineole has been used in products for oral hygiene.
In the case of filamentous fungi, Martins et al. [1] have shown that eucalyptus EO is toxic for M. hiemalis Wehmer, Alternaria alternata (Fr.) Keissl, Penicillium glabrum (Wehmer), and Fusarium roseum.
The main form of menthol occurring in nature is (−)-menthol, which is assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counter-irritant qualities.
Menthol’s analgesic properties are mediated through selective activation of κ-opioid receptors.
Menthol due to its properties provides relief, it is used on the skin for relief of itching and provides soothing sensation and hence used in topical applications for muscle pain relief. In addition, it is also helpful in reducing throat irritation, helps clearing up a blocked nose.
It’s also known to have smooth muscle-relaxing properties and hence used for abdominal pain due to smooth muscle spasm as seen in IBS and conditions which can cause spasm of the small and large intestine (bowel). It also helps with symptoms of bowel and bladder irritation, urgency, and hesitancy triggered by abnormal smooth muscle contractions in the bowel and bladder.
Menthol is the major constituent of peppermint oil, an herbal preparation commonly used to treat nausea, spasms during colonoscopy, and irritable bowel disease. The present results suggest that menthol induces spasmolytic effects in human colon circular muscle inhibiting directly the gastrointestinal smooth muscle contractility, through the block of Ca2+ influx through sarcolemma L-type Ca2+ channels. (Amato, Antonella et al., 2014).
Thymol (also known as 2-isopropyl-5-methylphenol, IPMP) is a natural monoterpenoid phenol derivative of cymene, C10H14O, isomeric with carvacrol, found in oil of thyme, and extracted from Thymus vulgaris (common thyme), Ajwain. (Nagoor Meeran et al.).
It has been shown to possess various pharmacological properties including antioxidant, free radical scavenging, anti-inflammatory, analgesic, antispasmodic, antibacterial, antifungal, antiseptic and antitumor activities-he pharmacological properties of thymol and its multiple therapeutic actions against various cardiovascular, neurological, rheumatological, gastrointestinal, metabolic and malignant diseases at both biochemical and molecular levels. The noteworthy effects of thymol are largely attributed to its anti-inflammatory (via inhibiting recruitment of cytokines and chemokines), antioxidant (via scavenging of free radicals, enhancing the endogenous enzymatic and non-enzymatic antioxidants and chelation of metal ions), antihyperlipidemic (via increasing the levels of high-density lipoprotein cholesterol and decreasing the levels of low-density lipoprotein cholesterol and low-density lipoprotein cholesterol in the circulation and membrane stabilization) (via maintaining ionic homeostasis).
Anti-inflammatory /Immunity boosting properties-Thymol (84 μg/ml) treatment attenuated lipopolysaccharide (LPS) and interferon-gamma (IFN-γ) induced macrophage inflammation.
In human polymorphonuclear neutrophils (PMNs), thymol (10 and 20 μg/ml) inhibited the synthetic chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced release of elastase, a marker of inflammatory diseases and a serine proteinase released by activated human neutrophils in a concentration-dependent manner.
Thymol (25–200 mg/kg) was shown to modulate the immune system in cyclosporine-A treated Swiss albino mice by enhancing the expressions of cluster of differentiation 4 (CD4), cluster of differentiation 8 (CD8) and Th1 cytokines via upregulation of IFN-γ expression and enhanced secretion of interleukin-12 (IL-12).
Anti-microbial Properties: Thymol at 2.5 mM inhibits the growth of S. aureus, E. coli, and S. Typhimurium. Furthermore, a synergistic interaction was found for thymol with all antibiotics tested against E. coli, S. Typhimurium, S. aureus, and S. pyogenes (Palaniappan and Holley, 2010). Thymol ester derivatives were found to be more effective against streptococcus species (Mathela et al., 2010). Thymol was found to possess antibacterial activity against selected verocytotoxigenic E. coli (Rivas et al., 2010). Thymol (0.12%) possess antifungal activity against C. albicans MTCC 227 biofilm inhibition (Pemmaraju et al., 2013). Gelatin films containing different thymol concentrations (1–8%) produced inhibitory zones ranging from 30 to 46 mm against several bacteria. Thymol was more effective against Gram-positive strains (Kavoosi et al., 2013). Thymol (15 and 30 mg/kg) was shown to possess cytotoxic and antileishmanial activities in hamsters experimentally infected with Leishmania (Viannia) panamensis (Robledo et al., 2005). Thymol derivative named benzoyl-thymol was the best inhibitor (8.67 ± 0.28 μg/mL) against Leishmania infantum chagasi (de Morais et al., 2014).
It is a terpenoid, It is found in the wood of the camphor laurel (Cinnamomum camphora), a large evergreen tree found in Asia.
Camphor exhibits a number of biological properties such as insecticidal, antimicrobial, antiviral, anticoccidial, anti-nociceptive, anticancer and antitussive activities, in addition to its use as a skin penetration enhancer.
Antibacterial: Significant activity of the essential oil was noted against the Gram-positive bacteria, Enterococcus hirae, as well as against the fungi Candida albicans and Saccharomyces cerevisiae.
Antiviral: Santolina insularis) essential oil, which is rich in camphor, deactivated herpes simplex type-1 (HSV-1) and type-2 (HSV-2) in vitro using plaque reduction assays with an IC50 value of 0.88 µg/mL for HSV-1 and 0.7 µg/mL for HSV-2. Reduction of plaque formation assays showed inhibition of cell-to-cell transmission of both HSV-1 and HSV-2 (Chen et al.).
The dyer’s alkanet or alkanet(Rang basa/ Ratan Jot ): is a herb in the borage family. Alkanna root can diminish the tight and slow mode of blood circulation which is the trigger of migraine and headache. By improving blood circulation, the headache will be relieved.
Alkanet root with its benefit as anti-inflammation also can be used to cure the inflammation of bones and muscles. It is traditionally used topically for the treatment of skin wounds and diseases. Orally, Alkanna root has been used for diarrhea and gastric ulcers. Alkanna root has demonstrated radical scavenging activity, suggesting potential anti-aging effects.